Ketorolac
A potent NSAID used for short-term management of moderate to severe pain, including postoperative pain and pain associated with certain cancers. It is available in oral, injectable, and nasal spray forms and works by blocking prostaglandin synthesis.
Peso molecular
255,2700 g/mol
LogP
1,90
TPSA
59,30 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Estructura 2D
Cite this structure
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SMILES
O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O
InChI
InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)
Molecular Formula
C15H13NO3
HBD / HBA
1 / 3
Enlaces Rotables
3
Átomos Pesados
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A potent NSAID used for short-term management of moderate to severe pain, including postoperative pain and pain associated with certain cancers. It is available in oral, injectable, and nasal spray forms and works by blocking prostaglandin synthesis.
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Yes, Ketorolac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL469. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3826. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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