Letrozole
A nonsteroidal aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women, and studied in other hormone-sensitive conditions. It works by blocking estrogen production to deprive cancer cells of the hormone they need to grow.
Peso molecular
285,3000 g/mol
LogP
2,70
TPSA
78,30 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1
InChI
InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
Molecular Formula
C17H11N5
HBD / HBA
- / 4
Enlaces Rotables
3
Átomos Pesados
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A nonsteroidal aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women, and studied in other hormone-sensitive conditions. It works by blocking estrogen production to deprive cancer cells of the hormone they need to grow.
Yes, Letrozole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1444. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3902. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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