Lomustine
An alkylating chemotherapy agent used to treat brain tumors and Hodgkin's lymphoma, taken orally every six weeks. It crosses the blood-brain barrier to damage DNA in cancer cells, preventing their replication.
Peso molecular
233,6900 g/mol
LogP
2,80
TPSA
61,80 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
O=NN(CCCl)C(=O)NC1CCCCC1
InChI
InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
Molecular Formula
C9H16ClN3O2
HBD / HBA
1 / 3
Enlaces Rotables
3
Átomos Pesados
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An alkylating chemotherapy agent used to treat brain tumors and Hodgkin's lymphoma, taken orally every six weeks. It crosses the blood-brain barrier to damage DNA in cancer cells, preventing their replication.
Yes, Lomustine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL514. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3950. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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