Maraviroc

CHEMBL256907 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

513.7 g/mol

LogP

5.1

Phase

4

A CCR5 antagonist antiretroviral medication used in combination with other HIV drugs to treat adults infected with CCR5-tropic HIV-1 by blocking the receptor the virus uses to enter immune cells. It requires a specific blood test to confirm the virus uses the CCR5 receptor before use.

Peso molecular

513,7000 g/mol

LogP

5,10

TPSA

63,10 Å²

Regla de cinco de Lipinski

No cumple

Áreas terapéuticas

Pancreatic Cancer Stroke Lymphoma HIV/AIDS Hepatitis C Cardiovascular Disease Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

Cc1nnc(C(C)C)n1[C@H]1C[C@H]2CC[C@@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

InChI

InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25+,26-/m0/s1

Molecular Formula

C29H41F2N5O

HBD / HBA

1 / 6

Enlaces Rotables

8

Átomos Pesados

37

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A CCR5 antagonist antiretroviral medication used in combination with other HIV drugs to treat adults infected with CCR5-tropic HIV-1 by blocking the receptor the virus uses to enter immune cells. It requires a specific blood test to confirm the virus uses the CCR5 receptor before use.

Yes, Maraviroc is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL256907. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3002977. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C29H41F2N5O
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.