Megestrol Acetate

CHEMBL1201139 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

384.5 g/mol

LogP

3.1

Phase

4

An acetate ester form of megestrol, a synthetic progestin used to treat certain breast and uterine cancers and to improve appetite and weight in patients experiencing cancer- or HIV-related weight loss.

Peso molecular

384,5000 g/mol

LogP

3,10

TPSA

60,40 Å²

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Cáncer colorrectal Cáncer de mama Cáncer de ovario Cáncer de páncreas Cáncer de próstata Cáncer de pulmón de células no pequeñas Cáncer de tiroides Cáncer de vejiga Enfermedad pulmonar obstructiva crónica Leucemia Linfoma Obesidad

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

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SMILES

CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

InChI

InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

Molecular Formula

C24H32O4

HBD / HBA

- / 4

Enlaces Rotables

3

Átomos Pesados

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

An acetate ester form of megestrol, a synthetic progestin used to treat certain breast and uterine cancers and to improve appetite and weight in patients experiencing cancer- or HIV-related weight loss.

Yes, Megestrol Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201139. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11683. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C24H32O4
Sinónimos: 2

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.