Metamizole
A non-opioid analgesic for severe pain, with rare agranulocytosis risk.
Peso molecular
311,3600 g/mol
LogP
0,00
TPSA
89,50 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …
Estructura 2D
Cite this structure
Embed this structure
SMILES
Cc1c(N(C)CS(=O)(=O)O)c(=O)n(-c2ccccc2)n1C
InChI
InChI=1S/C13H17N3O4S/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3,(H,18,19,20)
Molecular Formula
C13H17N3O4S
HBD / HBA
1 / 6
Enlaces Rotables
4
Átomos Pesados
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A non-opioid analgesic for severe pain, with rare agranulocytosis risk.
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Yes, Metamizole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL461522. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3111. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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