Methazolamide
A carbonic anhydrase inhibitor used to lower elevated intraocular (eye) pressure in people with glaucoma who cannot tolerate or do not respond adequately to other treatments. It helps prevent vision loss by reducing fluid buildup in the eye.
Peso molecular
236,3000 g/mol
LogP
0,10
TPSA
139,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Estructura 2D
Cite this structure
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SMILES
CC(=O)/N=c1/sc(S(N)(=O)=O)nn1C
InChI
InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
Molecular Formula
C5H8N4O3S2
HBD / HBA
1 / 6
Enlaces Rotables
1
Átomos Pesados
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A carbonic anhydrase inhibitor used to lower elevated intraocular (eye) pressure in people with glaucoma who cannot tolerate or do not respond adequately to other treatments. It helps prevent vision loss by reducing fluid buildup in the eye.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Methazolamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL19. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4100. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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