Nebivolol

CHEMBL434394 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

405.4 g/mol

LogP

3.0

Phase

4

This highly selective beta-blocker is used to treat high blood pressure and heart failure by slowing the heart rate and reducing the force of heart contractions. It also has unique blood vessel-relaxing properties that help lower blood pressure further.

Peso molecular

405,4000 g/mol

LogP

3,00

TPSA

71,00 Å²

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Cáncer de mama Diabetes tipo 2 Enfermedad cardiovascular Enfermedad pulmonar obstructiva crónica Enfermedad renal crónica Fibrilación auricular Glaucoma Hipertensión Ictus Insuficiencia cardíaca Linfoma Osteoporosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

OC(CNCC(O)C1CCc2cc(F)ccc2O1)C1CCc2cc(F)ccc2O1

InChI

InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2

Molecular Formula

C22H25F2NO4

HBD / HBA

3 / 7

Enlaces Rotables

6

Átomos Pesados

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

This highly selective beta-blocker is used to treat high blood pressure and heart failure by slowing the heart rate and reducing the force of heart contractions. It also has unique blood vessel-relaxing properties that help lower blood pressure further.

Yes, Nebivolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL434394. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71301. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C22H25F2NO4
Sinónimos: 2

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.