Netarsudil
This eye drop is used to lower elevated pressure inside the eye in patients with open-angle glaucoma or ocular hypertension. It works through a novel mechanism by reducing fluid production in the eye and improving fluid drainage, helping to prevent vision loss.
Peso molecular
453,5000 g/mol
LogP
4,60
TPSA
94,30 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
Cc1ccc(C(=O)OCc2ccc([C@@H](CN)C(=O)Nc3ccc4cnccc4c3)cc2)c(C)c1
InChI
InChI=1S/C28H27N3O3/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32)/t26-/m1/s1
Molecular Formula
C28H27N3O3
HBD / HBA
2 / 5
Enlaces Rotables
8
Átomos Pesados
34
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
This eye drop is used to lower elevated pressure inside the eye in patients with open-angle glaucoma or ocular hypertension. It works through a novel mechanism by reducing fluid production in the eye and improving fluid drainage, helping to prevent vision loss.
Yes, Netarsudil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594250. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 66599893. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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