Nicardipine

CHEMBL1484 Phase 4 Aprobado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
479.5 g/mol
LogP
3.8
Phase
4

A calcium channel blocker used to treat high blood pressure and certain types of chest pain by relaxing blood vessels.

Peso molecular

479,5000 g/mol

LogP

3,80

TPSA

114,00 Ų

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1

InChI

InChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3

Molecular Formula

C26H29N3O6

HBD / HBA

1 / 8

Enlaces Rotables

10

Átomos Pesados

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A calcium channel blocker used to treat high blood pressure and certain types of chest pain by relaxing blood vessels.

Yes, Nicardipine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1484. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4474. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.