Nitisinone
A medication used to treat hereditary tyrosinemia type 1 by blocking an enzyme in the tyrosine breakdown pathway.
Peso molecular
329,2300 g/mol
LogP
2,30
TPSA
97,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
InChI
InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
Molecular Formula
C14H10F3NO5
HBD / HBA
- / 8
Enlaces Rotables
2
Átomos Pesados
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A medication used to treat hereditary tyrosinemia type 1 by blocking an enzyme in the tyrosine breakdown pathway.
Yes, Nitisinone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1337. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 115355. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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