Novobiocin

CHEMBL36506 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

612.6 g/mol

LogP

3.3

Phase

4

An aminocoumarin antibiotic derived from Streptomyces that inhibits bacterial DNA gyrase, used to treat infections caused by Staphylococcus aureus and certain other gram-positive bacteria. It was also investigated in combination regimens for multidrug-resistant infections.

Peso molecular

612,6000 g/mol

LogP

3,30

TPSA

196,00 Å²

Regla de cinco de Lipinski

No cumple

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

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SMILES

CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C

InChI

InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1

Molecular Formula

C31H36N2O11

HBD / HBA

5 / 11

Enlaces Rotables

9

Átomos Pesados

44

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

An aminocoumarin antibiotic derived from Streptomyces that inhibits bacterial DNA gyrase, used to treat infections caused by Staphylococcus aureus and certain other gram-positive bacteria. It was also investigated in combination regimens for multidrug-resistant infections.

Yes, Novobiocin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL36506. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 54675769. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C31H36N2O11
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.