Palbociclib

CHEMBL189963 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

447.5 g/mol

LogP

1.8

Phase

4

This targeted cancer therapy is used to treat certain types of breast cancer by blocking proteins that help cancer cells multiply.

Peso molecular

447,5000 g/mol

LogP

1,80

TPSA

103,00 Å²

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Cáncer colorrectal Cáncer de mama Cáncer de ovario Cáncer de páncreas Cáncer de próstata Cáncer de pulmón de células no pequeñas Cáncer de tiroides Cáncer de vejiga Enfermedad cardiovascular Leucemia Linfoma Melanoma

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O

InChI

InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)

Molecular Formula

C24H29N7O2

HBD / HBA

2 / 8

Enlaces Rotables

5

Átomos Pesados

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

This targeted cancer therapy is used to treat certain types of breast cancer by blocking proteins that help cancer cells multiply.

Yes, Palbociclib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL189963. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5330286. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C24H29N7O2
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.