Pimecrolimus

CHEMBL1200686 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

810.4 g/mol

LogP

3.8

Phase

4

A non-steroidal cream used to treat mild to moderate eczema (atopic dermatitis) by calming the overactive immune response in the skin that causes redness, itching, and inflammation. It is often used in areas where steroid creams are not recommended, such as the face or skin folds.

Peso molecular

810,4000 g/mol

LogP

3,80

TPSA

158,00 Å²

Regla de cinco de Lipinski

No cumple

Áreas terapéuticas

Psoriasis Systemic Lupus Erythematosus Atopic Dermatitis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@H](Cl)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC

InChI

InChI=1S/C43H68ClNO11/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18,20,25,27-33,35-39,46,51H,10-17,19,21-23H2,1-9H3/b24-18+,26-20+/t25-,27+,28+,29-,30+,31-,32-,33-,35+,36-,37-,38+,39+,43+/m0/s1

Molecular Formula

C43H68ClNO11

HBD / HBA

2 / 11

Enlaces Rotables

6

Átomos Pesados

56

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A non-steroidal cream used to treat mild to moderate eczema (atopic dermatitis) by calming the overactive immune response in the skin that causes redness, itching, and inflammation. It is often used in areas where steroid creams are not recommended, such as the face or skin folds.

Yes, Pimecrolimus is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200686. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6509979. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C43H68ClNO11
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.