Pinacidil

CHEMBL1200338 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

263.3 g/mol

LogP

—

Phase

4

Pinacidil is a potassium channel opener of the cyanoguanidine class that activates ATP-sensitive potassium (K-ATP) channels in vascular smooth muscle, causing hyperpolarization, relaxation, and vasodilation. It was investigated as an antihypertensive agent and has been used experimentally in cardioprotection research, though it never achieved widespread clinical use.

Peso molecular

263,3400 g/mol

TPSA

74,10 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

CC(N/C(=N\C#N)Nc1ccncc1)C(C)(C)C.O

InChI

InChI=1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2

Molecular Formula

C13H21N5O

HBD / HBA

3 / 4

Enlaces Rotables

5

Átomos Pesados

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Pinacidil is a potassium channel opener of the cyanoguanidine class that activates ATP-sensitive potassium (K-ATP) channels in vascular smooth muscle, causing hyperpolarization, relaxation, and vasodilation. It was investigated as an antihypertensive agent and has been used experimentally in cardioprotection research, though it never achieved widespread clinical use.

Yes, Pinacidil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200338. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 55329. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C13H21N5O

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.