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Pramoxine Hydrochloride

CHEMBL1201171 Phase 4 Aprobado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
329.9 g/mol
LogP
—
Phase
4

Pramoxine hydrochloride is the hydrochloride salt form of pramoxine, a topical local anesthetic that blocks sodium channels in sensory nerves to provide temporary relief of pain and pruritus in minor skin conditions and anorectal disorders. See pramoxine for complete pharmacological details.

Peso molecular

329,9000 g/mol

TPSA

30,90 Ų

Mecanismo de acción

Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

Estructura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCCOc1ccc(OCCCN2CCOCC2)cc1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18;/h5-8H,2-4,9-15H2,1H3;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H28ClNO3

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Enlaces Rotables

                        
9

                    

                    
                    
                    

                        
Átomos Pesados

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Preguntas frecuentes

                

                    
                    

                        
                        

                            
Pramoxine hydrochloride is the hydrochloride salt form of pramoxine, a topical local anesthetic that blocks sodium channels in sensory nerves to provide temporary relief of pain and pruritus in minor skin conditions and anorectal disorders. See pramoxine for complete pharmacological details.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Pramoxine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201171.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 73957.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.