Procyclidine
Procyclidine is an anticholinergic antiparkinsonian agent that blocks muscarinic acetylcholine receptors in the striatum, thereby reducing the relative excess of cholinergic tone resulting from dopaminergic deficiency in Parkinson's disease and drug-induced parkinsonism. It is used for the management of tremor and rigidity in Parkinson's disease and for extrapyramidal side effects caused by antipsychotic medications.
Peso molecular
287,4000 g/mol
LogP
4,10
TPSA
23,50 Ų
Regla de cinco de Lipinski
Cumple
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
OC(CCN1CCCC1)(c1ccccc1)C1CCCCC1
InChI
InChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
Molecular Formula
C19H29NO
HBD / HBA
1 / 2
Enlaces Rotables
5
Átomos Pesados
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Procyclidine is an anticholinergic antiparkinsonian agent that blocks muscarinic acetylcholine receptors in the striatum, thereby reducing the relative excess of cholinergic tone resulting from dopaminergic deficiency in Parkinson's disease and drug-induced parkinsonism. It is used for the management of tremor and rigidity in Parkinson's disease and for extrapyramidal side effects caused by antipsychotic medications.
Yes, Procyclidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL86715. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4919. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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