Prussian Blue Insoluble
Prussian blue (insoluble ferric hexacyanoferrate) is an ion-exchange compound that binds radioactive cesium-137 and thallium ions with high affinity within the gastrointestinal tract, preventing their absorption and reabsorption, thereby accelerating their elimination via fecal excretion. It is approved as an antidote for internal contamination with radioactive cesium-137 and non-radioactive thallium, significantly reducing their biological half-lives.
Peso molecular
859,2000 g/mol
TPSA
428,00 Ų
Áreas terapéuticas
Mecanismo de acción
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
SMILES
[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+2].[Fe+2].[Fe+2].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
InChI
InChI=1S/18CN.7Fe/c18*1-2;;;;;;;/q18*-1;3*+2;4*+3
Molecular Formula
C18Fe7N18
HBD / HBA
- / 36
Enlaces Rotables
0
Átomos Pesados
43
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Prussian blue (insoluble ferric hexacyanoferrate) is an ion-exchange compound that binds radioactive cesium-137 and thallium ions with high affinity within the gastrointestinal tract, preventing their absorption and reabsorption, thereby accelerating their elimination via fecal excretion. It is approved as an antidote for internal contamination with radioactive cesium-137 and non-radioactive thallium, significantly reducing their biological half-lives.
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Yes, Prussian Blue Insoluble is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2096629. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2724251. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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