Pyrilamine

CHEMBL511 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

285.4 g/mol

LogP

3.3

Phase

4

Pyrilamine is a first-generation antihistamine of the ethylenediamine class that competitively antagonizes histamine H1 receptors, reducing allergic symptoms including rhinorrhea, sneezing, and pruritus, and also possesses significant anticholinergic and sedative properties. It is used in combination over-the-counter products for allergy, cold, and sleep aid formulations.

Peso molecular

285,4000 g/mol

LogP

3,30

TPSA

28,60 Å²

Regla de cinco de Lipinski

Cumple

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

COc1ccc(CN(CCN(C)C)c2ccccn2)cc1

InChI

InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3

Molecular Formula

C17H23N3O

HBD / HBA

- / 4

Enlaces Rotables

7

Átomos Pesados

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Pyrilamine is a first-generation antihistamine of the ethylenediamine class that competitively antagonizes histamine H1 receptors, reducing allergic symptoms including rhinorrhea, sneezing, and pruritus, and also possesses significant anticholinergic and sedative properties. It is used in combination over-the-counter products for allergy, cold, and sleep aid formulations.

Yes, Pyrilamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL511. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4992. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

¿Busca información accesible para el paciente?

Pyrilamine en PillFYI

Estructura

Datos Rápidos

Fórmula: C17H23N3O
Sinónimos: 50

Enlaces externos

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.