Rabeprazole

CHEMBL1219 Phase 4 Aprobado Small molecule
Half-Life
1-2 hours
Bioavailability
Protein Binding
Molecular Weight
359.4 g/mol
LogP
1.9
Phase
4

A proton pump inhibitor that reduces stomach acid production, used to treat gastroesophageal reflux disease, stomach ulcers, and related conditions. It provides relief from heartburn and helps the esophagus heal from acid damage.

Peso molecular

359,4440 g/mol

LogP

1,90

TPSA

96,30 Ų

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Clases de fármacos

Mecanismo de acción

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Pharmacokinetics (PK)

Half-Life 1-2 hours

Pharmacodynamics (PD)

Mecanismo

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Estructura 2D

SVG PNG

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SMILES

COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C

InChI

InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)

Molecular Formula

C18H21N3O3S

HBD / HBA

1 / 6

Enlaces Rotables

8

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A proton pump inhibitor that reduces stomach acid production, used to treat gastroesophageal reflux disease, stomach ulcers, and related conditions. It provides relief from heartburn and helps the esophagus heal from acid damage.

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Key pharmacokinetic parameters for Rabeprazole: Half-life: 1-2 hours.

Yes, Rabeprazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1219. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5029. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.