Raltegravir
An antiretroviral medication belonging to the integrase inhibitor class, used as part of combination therapy to treat HIV infection by preventing the virus from inserting its genetic material into human cells. It is effective against HIV strains resistant to other drug classes.
Peso molecular
444,4000 g/mol
LogP
1,10
TPSA
150,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.
Estructura 2D
Cite this structure
Embed this structure
SMILES
Cc1nnc(C(=O)NC(C)(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)o1
InChI
InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
Molecular Formula
C20H21FN6O5
HBD / HBA
3 / 9
Enlaces Rotables
6
Átomos Pesados
32
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An antiretroviral medication belonging to the integrase inhibitor class, used as part of combination therapy to treat HIV infection by preventing the virus from inserting its genetic material into human cells. It is effective against HIV strains resistant to other drug classes.
Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.
Yes, Raltegravir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL254316. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 54671008. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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