Relatlimab
Relatlimab is a human monoclonal antibody that inhibits lymphocyte activation gene-3 (LAG-3), an immune checkpoint receptor expressed on exhausted T cells that suppresses antitumor immune responses when engaged by MHC class II ligands. In combination with nivolumab (anti-PD-1), relatlimab provides dual checkpoint blockade that synergistically restores T-cell function against tumors, with approval for unresectable or metastatic melanoma.
Áreas terapéuticas
Mecanismo de acción
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Relatlimab is a human monoclonal antibody that inhibits lymphocyte activation gene-3 (LAG-3), an immune checkpoint receptor expressed on exhausted T cells that suppresses antitumor immune responses when engaged by MHC class II ligands. In combination with nivolumab (anti-PD-1), relatlimab provides dual checkpoint blockade that synergistically restores T-cell function against tumors, with approval for unresectable or metastatic melanoma.
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Yes, Relatlimab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3990044. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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