Reserpine
One of the oldest antihypertensive medications, derived from the Rauwolfia plant, which works by depleting norepinephrine and other neurotransmitters from nerve endings to lower blood pressure. It has largely been replaced by newer medications due to its side effect profile, including depression.
Peso molecular
608,7000 g/mol
LogP
4,00
TPSA
118,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
InChI
InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
Molecular Formula
C33H40N2O9
HBD / HBA
1 / 10
Enlaces Rotables
10
Átomos Pesados
44
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
One of the oldest antihypertensive medications, derived from the Rauwolfia plant, which works by depleting norepinephrine and other neurotransmitters from nerve endings to lower blood pressure. It has largely been replaced by newer medications due to its side effect profile, including depression.
Yes, Reserpine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL772. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5770. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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