Retapamulin
A topical antibiotic ointment used to treat impetigo and other minor bacterial skin infections caused by Staphylococcus and Streptococcus bacteria. It works through a unique mechanism of action that makes cross-resistance with other antibiotics unlikely.
Peso molecular
517,8000 g/mol
LogP
6,10
TPSA
92,10 Ų
Regla de cinco de Lipinski
No cumple
Áreas terapéuticas
Mecanismo de acción
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estructura 2D
Cite this structure
Embed this structure
SMILES
C=C[C@]1(C)C[C@@H](OC(=O)CS[C@@H]2C[C@H]3CC[C@@H](C2)N3C)[C@]2(C)[C@H](C)CC[C@]3(CCC(=O)[C@H]32)[C@@H](C)[C@@H]1O
InChI
InChI=1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22-,24-,26+,27+,28-,29+,30+/m1/s1
Molecular Formula
C30H47NO4S
HBD / HBA
1 / 6
Enlaces Rotables
6
Átomos Pesados
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A topical antibiotic ointment used to treat impetigo and other minor bacterial skin infections caused by Staphylococcus and Streptococcus bacteria. It works through a unique mechanism of action that makes cross-resistance with other antibiotics unlikely.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Retapamulin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1658. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6918462. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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