Rituximab
A monoclonal antibody that targets the CD20 protein on B cells, used to treat various B-cell lymphomas, leukemias, and autoimmune conditions like rheumatoid arthritis. It depletes CD20-positive B cells through multiple immune mechanisms, including antibody-dependent cellular cytotoxicity.
Áreas terapéuticas
Clases de fármacos
Mecanismo de acción
Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A monoclonal antibody that targets the CD20 protein on B cells, used to treat various B-cell lymphomas, leukemias, and autoimmune conditions like rheumatoid arthritis. It depletes CD20-positive B cells through multiple immune mechanisms, including antibody-dependent cellular cytotoxicity.
Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.
Key pharmacokinetic parameters for Rituximab: Half-life: 22 days.
Yes, Rituximab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201576. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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