Sildenafil Citrate
A citrate salt form of sildenafil with the same therapeutic properties. Originally developed for heart conditions, this medication relaxes and widens blood vessels by blocking an enzyme called PDE5, increasing blood flow.
Peso molecular
666,7000 g/mol
TPSA
250,00 Ų
Áreas terapéuticas
Mecanismo de acción
Selective PDE5 inhibitor increasing cGMP.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selective PDE5 inhibitor increasing cGMP.
Estructura 2D
Cite this structure
Embed this structure
SMILES
CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12.O=C(O)CC(O)(CC(=O)O)C(=O)O
InChI
InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
Molecular Formula
C28H38N6O11S
HBD / HBA
5 / 15
Enlaces Rotables
12
Átomos Pesados
46
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A citrate salt form of sildenafil with the same therapeutic properties. Originally developed for heart conditions, this medication relaxes and widens blood vessels by blocking an enzyme called PDE5, increasing blood flow.
Selective PDE5 inhibitor increasing cGMP.
Yes, Sildenafil Citrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1737. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 135413523. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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