Sulfisomidine

CHEMBL485696 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

278.3 g/mol

LogP

1.2

Phase

4

Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

Peso molecular

278,3300 g/mol

LogP

1,20

TPSA

106,00 Å²

Regla de cinco de Lipinski

Cumple

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1

InChI

InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

Molecular Formula

C12H14N4O2S

HBD / HBA

2 / 6

Enlaces Rotables

3

Átomos Pesados

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

Yes, Sulfisomidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL485696. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5343. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C12H14N4O2S

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.