Talbutal

CHEMBL1200802 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

224.3 g/mol

LogP

1.4

Phase

4

Talbutal is an intermediate-acting barbiturate that acts on GABA-A receptors to enhance chloride ion influx, producing central nervous system depression. It was historically used as a sedative and hypnotic agent for the short-term treatment of insomnia. Due to its high abuse potential, tolerance development, and risk of fatal overdose, it has largely been replaced by safer alternatives.

Peso molecular

224,2600 g/mol

LogP

1,40

TPSA

75,30 Å²

Regla de cinco de Lipinski

Cumple

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

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SMILES

C=CCC1(C(C)CC)C(=O)NC(=O)NC1=O

InChI

InChI=1S/C11H16N2O3/c1-4-6-11(7(3)5-2)8(14)12-10(16)13-9(11)15/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16)

Molecular Formula

C11H16N2O3

HBD / HBA

2 / 3

Enlaces Rotables

4

Átomos Pesados

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Talbutal is an intermediate-acting barbiturate that acts on GABA-A receptors to enhance chloride ion influx, producing central nervous system depression. It was historically used as a sedative and hypnotic agent for the short-term treatment of insomnia. Due to its high abuse potential, tolerance development, and risk of fatal overdose, it has largely been replaced by safer alternatives.

Yes, Talbutal is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200802. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 8275. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Talbutal en PillFYI

Estructura

Datos Rápidos

Fórmula: C11H16N2O3

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.