Telmisartan

CHEMBL1017 Phase 4 Aprobado Small molecule
Half-Life
24 hours
Bioavailability
Protein Binding
Molecular Weight
514.6 g/mol
LogP
6.9
Phase
4

This medication belongs to the angiotensin receptor blocker (ARB) class and is used to treat high blood pressure and to reduce the risk of heart attack and stroke in high-risk patients. It works by blocking the action of a hormone called angiotensin II, which normally tightens blood vessels. It is taken once daily and is generally well tolerated.

Peso molecular

514,6230 g/mol

LogP

6,90

TPSA

72,90 Ų

Regla de cinco de Lipinski

No cumple

Áreas terapéuticas

Clases de fármacos

Mecanismo de acción

Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Pharmacokinetics (PK)

Half-Life 24 hours

Pharmacodynamics (PD)

Mecanismo

Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Estructura 2D

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SMILES

CCCc1nc2c(C)cc(-c3nc4ccccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

InChI

InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)

Molecular Formula

C33H30N4O2

HBD / HBA

1 / 4

Enlaces Rotables

7

Átomos Pesados

39

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

This medication belongs to the angiotensin receptor blocker (ARB) class and is used to treat high blood pressure and to reduce the risk of heart attack and stroke in high-risk patients. It works by blocking the action of a hormone called angiotensin II, which normally tightens blood vessels. It is taken once daily and is generally well tolerated.

Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Key pharmacokinetic parameters for Telmisartan: Half-life: 24 hours.

Yes, Telmisartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1017. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 65999. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.