Tenofovir Disoproxil Maleate
Tenofovir disoproxil maleate is the maleate salt form of tenofovir disoproxil, a prodrug NRTI used for HIV-1 and hepatitis B treatment. See tenofovir-disoproxil for complete pharmacological details. This alternative salt form has been studied as a pharmaceutical development option.
Peso molecular
635,5000 g/mol
TPSA
260,00 Ų
Mecanismo de acción
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Estructura 2D
Cite this structure
Embed this structure
SMILES
CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)OCOC(=O)OC(C)C.O=C(O)/C=C\C(=O)O
InChI
InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-;/m1./s1
Molecular Formula
C23H34N5O14P
HBD / HBA
3 / 18
Enlaces Rotables
19
Átomos Pesados
43
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Tenofovir disoproxil maleate is the maleate salt form of tenofovir disoproxil, a prodrug NRTI used for HIV-1 and hepatitis B treatment. See tenofovir-disoproxil for complete pharmacological details. This alternative salt form has been studied as a pharmaceutical development option.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Tenofovir Disoproxil Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068332. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 86280652. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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