Tipiracil Hydrochloride

CHEMBL65375 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

279.1 g/mol

LogP

—

Phase

4

Tipiracil hydrochloride is the hydrochloride salt form of tipiracil, a thymidine phosphorylase inhibitor combined with trifluridine for treatment of refractory colorectal cancer. See tipiracil for complete pharmacological details. This salt formulation is used in the approved fixed-dose oral combination product.

Peso molecular

279,1200 g/mol

TPSA

85,30 Å²

Áreas terapéuticas

Pancreatic Cancer Bladder Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

Cl.N=C1CCCN1Cc1[nH]c(=O)[nH]c(=O)c1Cl

InChI

InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H

Molecular Formula

C9H12Cl2N4O2

HBD / HBA

4 / 3

Enlaces Rotables

2

Átomos Pesados

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Tipiracil hydrochloride is the hydrochloride salt form of tipiracil, a thymidine phosphorylase inhibitor combined with trifluridine for treatment of refractory colorectal cancer. See tipiracil for complete pharmacological details. This salt formulation is used in the approved fixed-dose oral combination product.

Yes, Tipiracil Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL65375. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9903778. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estructura

Datos Rápidos

Fórmula: C9H12Cl2N4O2

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.