Bupropion vs Sitagliptin

## Bupropion vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Bupropion** and **Sitagliptin**.

## Mechanism of Action

**Bupropion**: Norepinephrine-dopamine reuptake inhibitor (NDRI).

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Bupropion — 21 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Bupropion — C13H18ClNO; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Bupropion — 239.7420 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Bupropion — Small molecule; Sitagliptin — Small molecule.