Canagliflozin vs Spironolactone

## Canagliflozin vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Canagliflozin** and **Spironolactone**.

## Mechanism of Action

**Canagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Canagliflozin — 10.6 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Canagliflozin — C24H25FO5S; Spironolactone — C24H32O4S.

**Molecular Weight**: Canagliflozin — 444.5170 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Canagliflozin — Small molecule; Spironolactone — Small molecule.