Candesartan vs Sildenafil

## Candesartan vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Candesartan** and **Sildenafil**.

## Mechanism of Action

**Candesartan**: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Candesartan — 9 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Candesartan — C33H34N6O6; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Candesartan — 610.6640 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Candesartan — Small molecule; Sildenafil — Small molecule.