Captopril vs Furosemide

## Captopril vs Furosemide: Overview

This comparison examines the pharmacological differences between **Captopril** and **Furosemide**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Furosemide**: Loop diuretic inhibiting Na-K-2Cl cotransporter.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Furosemide — 2 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Furosemide — C12H11ClN2O5S.

**Molecular Weight**: Captopril — 217.2850 g/mol; Furosemide — 330.7440 g/mol.

**Type**: Captopril — Small molecule; Furosemide — Small molecule.