Captopril vs Ibuprofen

## Captopril vs Ibuprofen: Overview

This comparison examines the pharmacological differences between **Captopril** and **Ibuprofen**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Ibuprofen — 2-4 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Ibuprofen — C13H18O2.

**Molecular Weight**: Captopril — 217.2850 g/mol; Ibuprofen — 206.2810 g/mol.

**Type**: Captopril — Small molecule; Ibuprofen — Small molecule.