Captopril vs Loratadine

## Captopril vs Loratadine: Overview

This comparison examines the pharmacological differences between **Captopril** and **Loratadine**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Captopril — 217.2850 g/mol; Loratadine — 382.8800 g/mol.

**Type**: Captopril — Small molecule; Loratadine — Small molecule.