Celecoxib vs Loratadine

## Celecoxib vs Loratadine: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Loratadine**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Loratadine — 382.8800 g/mol.

**Type**: Celecoxib — Small molecule; Loratadine — Small molecule.