Celecoxib vs Sildenafil

## Celecoxib vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Sildenafil**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Celecoxib — Small molecule; Sildenafil — Small molecule.