Dexamethasone vs Diphenhydramine

## Dexamethasone vs Diphenhydramine: Overview

This comparison examines the pharmacological differences between **Dexamethasone** and **Diphenhydramine**.

## Mechanism of Action

**Dexamethasone**: Potent synthetic glucocorticoid.

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

## Pharmacokinetics

**Half-life**: Dexamethasone — 36-54 hours; Diphenhydramine — 2-8 hours.

## Chemical Properties

**Molecular Formula**: Dexamethasone — C22H29FO5; Diphenhydramine — C17H21NO.

**Molecular Weight**: Dexamethasone — 392.4610 g/mol; Diphenhydramine — 255.3550 g/mol.

**Type**: Dexamethasone — Small molecule; Diphenhydramine — Small molecule.