Diazepam vs Loratadine

## Diazepam vs Loratadine: Overview

This comparison examines the pharmacological differences between **Diazepam** and **Loratadine**.

## Mechanism of Action

**Diazepam**: Positive allosteric modulator of GABA-A receptors.

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Diazepam — 20-100 hours; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Diazepam — C16H13ClN2O; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Diazepam — 284.7400 g/mol; Loratadine — 382.8800 g/mol.

**Type**: Diazepam — Small molecule; Loratadine — Small molecule.