Digoxin vs Trimethoprim

## Digoxin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Digoxin** and **Trimethoprim**.

## Mechanism of Action

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Digoxin — 36-48 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Digoxin — C41H64O14; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Digoxin — 780.9430 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Digoxin — Small molecule; Trimethoprim — Small molecule.