Empagliflozin vs Sitagliptin

## Empagliflozin vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Empagliflozin** and **Sitagliptin**.

## Mechanism of Action

**Empagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Empagliflozin — 12.4 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Empagliflozin — C23H27ClO7; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Empagliflozin — 450.9100 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Empagliflozin — Small molecule; Sitagliptin — Small molecule.