Fentanyl vs Sildenafil

## Fentanyl vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Fentanyl** and **Sildenafil**.

## Mechanism of Action

**Fentanyl**: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Fentanyl — 2-4 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Fentanyl — C22H28N2O; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Fentanyl — 336.4700 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Fentanyl — Small molecule; Sildenafil — Small molecule.