Fluoxetine vs Tofacitinib

## Fluoxetine vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Fluoxetine** and **Tofacitinib**.

## Mechanism of Action

**Fluoxetine**: Selective serotonin reuptake inhibitor (SSRI).

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Fluoxetine — 1-3 days; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Fluoxetine — C17H18F3NO; Tofacitinib — C16H20N6O.

**Molecular Weight**: Fluoxetine — 309.3260 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Fluoxetine — Small molecule; Tofacitinib — Small molecule.