Gabapentin vs Lamotrigine

## Gabapentin vs Lamotrigine: Overview

This comparison examines the pharmacological differences between **Gabapentin** and **Lamotrigine**.

## Mechanism of Action

**Gabapentin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

**Lamotrigine**: Sodium channel blocker inhibiting glutamate release.

## Pharmacokinetics

**Half-life**: Gabapentin — 5-7 hours; Lamotrigine — 25 hours.

## Chemical Properties

**Molecular Formula**: Gabapentin — C9H17NO2; Lamotrigine — C9H7Cl2N5.

**Molecular Weight**: Gabapentin — 171.2370 g/mol; Lamotrigine — 256.0910 g/mol.

**Type**: Gabapentin — Small molecule; Lamotrigine — Small molecule.