Hydrochlorothiazide vs Ibuprofen

## Hydrochlorothiazide vs Ibuprofen: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Ibuprofen**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Ibuprofen — 2-4 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Ibuprofen — C13H18O2.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Ibuprofen — 206.2810 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Ibuprofen — Small molecule.