Hydrochlorothiazide vs Tamsulosin

## Hydrochlorothiazide vs Tamsulosin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Tamsulosin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Tamsulosin**: Selective alpha-1A adrenergic receptor antagonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Tamsulosin — 10-13 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Tamsulosin — C20H28N2O5S.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Tamsulosin — 408.5100 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Tamsulosin — Small molecule.