Irbesartan vs Sitagliptin

## Irbesartan vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Irbesartan** and **Sitagliptin**.

## Mechanism of Action

**Irbesartan**: Selective non-competitive angiotensin II type 1 receptor antagonist.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Irbesartan — 11-15 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Irbesartan — C25H28N6O; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Irbesartan — 428.5320 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Irbesartan — Small molecule; Sitagliptin — Small molecule.