Nivolumab vs Sitagliptin

## Nivolumab vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Nivolumab** and **Sitagliptin**.

## Mechanism of Action

**Nivolumab**: Fully human anti-PD-1 IgG4 monoclonal antibody restoring T-cell anti-tumor activity.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Nivolumab — 27 days; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Nivolumab — N/A; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Nivolumab — N/A; Sitagliptin — 407.3140 g/mol.

**Type**: Nivolumab — Antibody; Sitagliptin — Small molecule.